KPV 5mg | Lysine-Proline-Valine Tripeptide | ≥99% Purity (HPLC)
KPV is a potent tripeptide (Lys-Pro-Val) derived from alpha-melanocyte-stimulating hormone (α-MSH), renowned for its strong anti-inflammatory, antimicrobial, and wound-healing properties. This short, stable peptide is widely researched for its ability to modulate immune responses, promote tissue repair, and exert protective effects across various inflammatory and mucosal models.
Research investigations have demonstrated KPV’s potential to:
- Reduce pro-inflammatory cytokine production (e.g., TNF-α, IL-1β, IL-6)
- Inhibit NF-κB signaling pathways
- Accelerate wound healing and epithelial repair
- Exhibit antimicrobial activity against pathogens
- Protect gastrointestinal mucosa in models of IBD/colitis
- Suppress inflammatory responses in skin, gut, and ocular tissues
- Support resolution of chronic inflammation without immunosuppression
KPV is of significant interest in inflammatory bowel disease (IBD), dermatology, wound repair, and mucosal protection research due to its targeted anti-inflammatory profile and excellent safety in preclinical studies.
For Research Use Only. Not for human consumption, diagnostic, therapeutic, or veterinary purposes. Strictly intended for in vitro laboratory research by qualified professionals.
Specifications:
- Sequence: Lys-Pro-Val (KPV)
- Molecular Formula: C₁₆H₃₀N₄O₄
- Molecular Weight: 342.43 Da
- Appearance: White lyophilized powder
- Purity: ≥99% (HPLC)
- Solubility: Water-soluble
- Storage: Lyophilized at -20°C; reconstituted at 2–8°C short-term. Protect from light and moisture.
Common Research Areas: Anti-inflammatory mechanisms • IBD/colitis models • Wound healing • Mucosal protection • Antimicrobial peptides • Immune modulation • NF-κB inhibition • Dermatological inflammation






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