TB500 10mg

TB-500 10mg | Thymosin Beta-4 Fragment | ≥99% Purity (HPLC)

TB-500 is a synthetic peptide consisting of a biologically active fragment (Ac-LKKTETQ) of the naturally occurring 43-amino acid protein Thymosin Beta-4 (Tβ4). This actin-sequestering peptide is extensively studied for its role in regulating actin polymerization, promoting cell migration, angiogenesis, and tissue repair processes.

Research investigations have highlighted TB-500’s potential to:

• Accelerate wound healing and tissue regeneration
• Enhance cellular migration and proliferation
• Promote new blood vessel formation (angiogenesis)
• Reduce inflammation and oxidative stress
• Support musculoskeletal recovery, including tendons, ligaments, and muscles
• Exhibit cardioprotective and neuroprotective effects in preclinical models
• Modulate anti-fibrotic pathways

TB-500 is of significant interest in regenerative biology, injury recovery models, and studies on systemic tissue remodeling due to its ability to upregulate actin dynamics and influence growth factor signaling.

For Research Use Only. Not for human consumption, diagnostic, therapeutic, or veterinary purposes. Strictly intended for in vitro laboratory research by qualified professionals.

Specifications:

• Sequence: Ac-LKKTETQ
• Molecular Formula: C₃₈H₆₈N₁₄O₁₄S (active fragment)
• Molecular Weight: ≈889 Da (fragment); full TB-500 often referenced at ~4,963 Da
• Appearance: White lyophilized powder
• Purity: ≥99% (HPLC)
• Solubility: Water-soluble
• Storage: Lyophilized at -20°C; reconstituted at 2–8°C short-term. Protect from light and moisture.

Common Research Areas: Tissue regeneration • Wound healing • Angiogenesis • Anti-inflammatory mechanisms • Musculoskeletal repair • Cardiovascular protection • Actin regulation